Laser treatment is generally ineffective for macular lentigines. Currently, surgical intervention is often required for this disease, and the specific treatment modality is related to the patient’s condition. Currently, surgical treatment is the main intervention for macular schisis, and commonly used procedures include vitrectomy, endothelial membrane peeling, autologous endothelial membrane transplantation, etc. Macular schisis is generally not treated by laser therapy. In addition, it should be noted that in ophthalmology, laser treatment is commonly used to treat myopia, glaucoma, vitreous clouding, retinal detachment, etc. However, this treatment is still prohibited in the presence of severe dry eye, severe amblyopia, recurring viral keratitis, etc. There is also the possibility of adverse reactions such as dryness of the eyes and nighttime glare after the treatment. Patients with macular lentigines are advised to seek timely medical attention to evaluate their condition and choose the appropriate treatment under the guidance of their doctor.