After radiotherapy for nasopharyngeal cancer, calcification appeared in review, suggesting damage to nasal mucosa. Nasopharyngeal cancer patients take radiotherapy with relatively big side effects, and some patients may have gastrointestinal reactions during treatment, including nausea, vomiting, loss of appetite and so on. If the nasal mucosa is stimulated for a long time, the mucosal tissue may be damaged, and through examination, it will be found that long-term radiotherapy leads to calcification of nasal mucosa. If it is a relatively small calcification, it usually has little effect and can be removed after removing the lesion in the nose; however, if it is a relatively large calcification, it is necessary to pay attention to nasal hygiene during the treatment period to prevent secondary infection, and surgery can be done to remove it if necessary. The purpose of radiotherapy for nasopharyngeal cancer patients is to improve the quality of life and prolong the survival rate, which should be carried out in strict compliance with the doctor’s prescription, and consult the doctor in time if there is any adverse reaction.