Ursodeoxycholic acid is a common drug used in clinical practice for cholesterol gallbladder stones, cholestatic disease and bile reflux gastritis. Generally, if it is used to treat cholesterol gallbladder stones and cholestasis, it should be taken for 6-24 months. If the stones are not significantly smaller after 12 months, it is necessary to stop taking it, and the ultrasound of liver, gallbladder, pancreas and spleen should be checked every six months during the period of taking it. Ursodeoxycholic acid also has certain side effects and may cause damage to liver function, so it is necessary to review liver function regularly while taking it.