The treatment of sinusitis drugs are more, such as intranasal decongestants, nasal glucocorticoids, antibiotics, mucolytic agents, anti-allergic drugs, etc., according to the cause of the disease and the specific conditions of the standardized use, in order to play a better therapeutic effect. 1. Intranasal decongestants: commonly used drugs are furosemide nasal drops, seroquel nasal spray. Can be used to reduce the phenomenon of nasal and sinus mucosal swelling, thus improving sinus drainage, but need to avoid long-term use, so as not to lead to the emergence of drug rhinitis. 2. Nasal glucocorticoid: it is the first choice of local drugs for the treatment of sinusitis, such as budesonide, fluticasone propionate, etc., which can reduce the inflammatory reaction of the nasal mucosa, and it is easy to cause rhinorrhea and coughing and other adverse reactions. 3. Antibiotics: can be used to control the infection and prevent the emergence of complications, generally need to identify the causative organisms and select sensitive antibiotic drugs, if not clear causative organisms, broad-spectrum antibiotics, such as cephalosporin, penicillin, etc.; clear anaerobic bacteria can be used tinidazole, metronidazole and other treatments. 4. Mucolytic agents: can play a role in thinning nasal and sinus secretions, improve the role of nasal mucosal cilia activity, commonly used drugs are eucalyptus-pinocampus soft capsule, oleander drops and so on. 5. Anti-allergic drugs: for patients with allergic rhinitis or asthma, antihistamines can be used for treatment, such as loratadine benzylamine, etc., which can play the role of anti-allergy and reduce inflammation. The choice of specific drugs, need to standardize the treatment under the guidance of a professional doctor.