High erythrocyte volume distribution width refers to blood erythrocytes of varying shapes and sizes, and is often analyzed in conjunction with the erythrocyte volume parameter, which is important for the differential diagnosis of anemia.
High erythrocyte volume distribution width and low erythrocyte volume suggest iron deficiency anemia, while high erythrocyte volume distribution width and increased erythrocyte volume are seen in megaloblastic anemia.
1. Iron deficiency anemia: belongs to microcytic hypochromic anemia, due to insufficient iron storage in the body, hemoglobin synthesis is reduced, the volume of erythrocyte becomes small, thus the distribution width of erythrocyte increases during the latent period of iron deficiency, and if the anemia is corrected, the distribution width of erythrocyte gradually decreases.
2. Megaloblastic anemia: due to the lack of vitamin B12 and folic acid, the hematopoietic system is abnormal, the volume of red blood cells is abnormal, and megaloblastic change occurs, the volume of red blood cells increases, which leads to the abnormally high distribution width of red blood cells.
If the examination of the red blood cell volume distribution widening, it is recommended to further consult the doctor to clarify the diagnosis and then treatment.