Total protein represents the overall value of albumin and globulin in serum. The determination of total protein in serum is one of the important items in clinical biochemical testing, which can be used to determine the nutritional status of the body, and plays an important role in the diagnosis and treatment of nephrotic syndrome, cirrhosis and other diseases. Total protein, which can be divided into albumin and globulin, has important physiological functions in the body. Serum proteins have a variety of functions such as maintaining blood osmotic pressure, regulating the physiological effects of passively transported substances and relieving their toxicity, immune effects and nutritional effects. Increased total protein can be seen in vomiting, diarrhea, high fever and other water loss caused by blood concentration; multiple myeloma, macroglobulinemia, systemic lupus erythematosus, multiple sclerosis and so on. Decreased total protein can be seen in malignant tumors, severe tuberculosis, hyperthyroidism, late pregnancy, nephrotic syndrome, chronic gastrointestinal diseases, ulcerative colitis, cirrhosis, protein-losing enteropathy and other diseases. If you want to check the level of total protein, you can go to the hospital to improve the blood sampling blood biochemistry or emergency full and so on further understanding.