Medication abortion involves taking two medications in the clinic, one is mifepristone tablets and the other is misoprostol. The vast majority of people will not experience lower abdominal pain while taking mifepristone tablets, about 1% of people who will have a miscarriage while taking mifepristone will experience lower abdominal pain, this pain lasts for about 20 minutes or so. The vast majority of people who have a medicated abortion will have lower abdominal pain only after taking misoprostol, and this pain lasts for about 20 minutes. The products of pregnancy are expelled about 2-6 hours after taking misoprostol, so it is important to give close clinical observation, and if the products of pregnancy are expelled, be sure to let your doctor know if the expulsion is complete and if it has been cleared.