Biliary atresia is the most common cause of persistent jaundice in newborns and can be seen on ultrasound. Biliary atresia may be associated with congenital developmental malformations, chromosomal abnormalities, or with viral infections, inflammatory reactions, etc. It consists of three types, type I is choledochal atresia, type II is hepatobiliary atresia, and type III is biliary atresia of the hepatic hilum, and the main manifestations of this condition are jaundice, malnutrition and dysplasia, and hepatosplenomegaly. Differential diagnosis can be made by ultrasonography, magnetic resonance cholangiopancreatography (MRCP), transendoscopic retrograde cholangiopancreatography (ERCP), and color ultrasound can reveal biliary atresia. Surgery is the only treatment for patients with biliary atresia, which should be performed two months after birth for newborns, with daily attention to diet, avoiding spicy and stimulating foods, rest, and appropriate physical exercise.