Vaccination currently refers mostly to the Neocoronavirus vaccine. Nucleic acid testing within 24 hours of vaccination generally has no effect on the results, but there is a very low probability that it may result in a false-positive test result.
Nucleic acid testing checks for the presence of neocoronavirus nucleic acid in the subject’s nasopharyngeal swab. Neocoronavirus vaccine is an antigenic biological agent, which is based on the principle that inactivating Neocoronavirus or recombining some components of Neocoronavirus into other cells makes it immunogenic but not antigenic, and then induces the body to produce antibodies.
Aerosols may be formed during the Neocoronavirus vaccination process, causing vaccine residue in the mouth or some areas, which may result in a positive test result, but the probability of this is low. Therefore, nucleic acid testing 24 hours after administration of New Crown Vaccine may result in a false-positive nucleic acid test. If other types of vaccines are administered, there is no effect on the nucleic acid result.
This positive result is not due to infection of the organism with NeoCoronavirus, but due to vaccine residues, and therefore it is recommended that the nucleic acid test be performed 48 hours after vaccination.