There are more reasons for knee pain when doing squats, such as knee osteoarthritis, ligament injuries, meniscus injuries, chondromalacia patellae, and so on. Recovery methods need to be based on the specific cause of the disease, such as general treatment, physical therapy (hot compresses), drug therapy (ibuprofen, etc.) and surgical treatment. 1. Knee arthritis: the more common ones are osteoarthritis, rheumatoid arthritis, etc. It is necessary to pay attention to rest, avoid strenuous exercise, and the knee joint can be appropriately warmed up, and non-steroidal anti-inflammatory drugs such as ibuprofen can be given when necessary, and intra-articular injection of sodium vitrate can be used to lubricate the joint cavity. Knee joint wear and tear is serious, can be surgical treatment, such as knee arthroplasty. 2. Ligament injury: If the ligaments in the knee joint are strained, pain can occur when squatting. If the pain is mild, it can be recovered gradually after resting; if the pain is severe, it can be treated with diclofenac sodium and other medicines for pain relief; if the pain is serious, it can be treated with suture surgery. 3. Meniscus injury: Mild cases can recover after rest and hot compresses. In severe cases, conservative treatment is ineffective, but also need to give surgical treatment, such as arthroscopic meniscus suture surgery. 4. Chondromalacia patella: conservative treatment, in addition to rest and appropriate hot compresses, can use non-steroidal anti-inflammatory drugs, such as ibuprofen, etc., can also use glucosamine. Lubricants such as sodium vitrate can also be injected into the joint cavity. When conservative treatment is ineffective, arthroscopic lesion excision can be performed. It is recommended that the patient go to the hospital for consultation to clarify the condition, and be given appropriate treatment by a professional physician, and the drugs need to be used under the guidance of a professional physician.