Foot neuralgia may be caused by diabetic peripheral neuropathy, neuritis, etc. It can be treated by lowering blood glucose and other symptomatic treatments, as well as nutritional nerve, pain relief and other symptomatic treatments. For those caused by drug poisoning, it is necessary to stop the treatment. 1. Diabetic peripheral neuropathy: the symptoms of foot pain may occur, and the symptoms of pain can be relieved by oral metformin and other hypoglycemic drugs, or by injecting insulin to control blood glucose and then delay neuropathy. Nutritional drugs such as Epalrestat and methylcobalamin can also be used. 2. Neuritis: For patients with severe pain caused by neuritis, ibuprofen and methylcobalamin can be used to relieve the symptoms of pain. In addition, the cause of the pain needs to be treated, such as immunoglobulin injections and B vitamins supplementation for patients with Guillain-Barre syndrome. 3. Other: for phenytoin sodium and other drug poisoning caused by the need to stop using drugs, and timely consultation. When the foot pain, should go to the regular hospital, clear cause and follow the doctor’s instructions for treatment, do not blindly use drugs.