Glucophage, also known as gliquidone, is mainly used for the treatment of type 2 diabetes mellitus, that is, non-insulin-dependent diabetes mellitus, and is a sulfonylurea insulinotropic agent, which is usually recommended to be taken half an hour before a meal, with a daily dose of 15-120 mg, that is, half a tablet to four tablets, but also according to the individual situation, as well as blood glucose, appropriate to adjust the dose of the drug. The usual daily dose may also be 30mg, or one tablet, which can be taken before breakfast. For larger doses, they should be taken separately before meals, but the maximum daily dose should not exceed 180mg, or six tablets. Adverse reactions commonly seen with SugarSmart include skin allergic reactions, gastrointestinal reactions, hypoglycemic reactions, and hematologic reactions. If diabetic patients combined with renal dysfunction, generally mild renal dysfunction can be oral Sucralfate. But when combined with severe renal insufficiency, it is recommended to take insulin treatment.