The value of alkaline phosphatase in children is highly dependent on age. In general, it is less than 500 units per liter for children aged 1-12 years and less than 750 units per liter for children aged 12-15 years. Since alkaline phosphatase is closely related to diseases of the skeletal and hepatobiliary systems, it is often used clinically as an important basis for differentiation and diagnosis of these two diseases. As children secrete a large amount of alkaline phosphatase during skeletal development, it can increase the blood alkaline phosphatase level, so this increase is a normal physiological phenomenon. If there is an abnormal increase, the following causes should be considered: first, jaundice of primary color, secondary and primary liver cancer, and cholestatic hepatitis. Second, the recovery period of fracture. Third, chondromalacia and rickets and other bone diseases. IV. Kidney disease, severe anemia or leukemia. The above content is for reference only, please refer to the doctor’s guidance for specific medication and treatment.