Pancreatic body tail fullness is an increase in the volume of the tail of the pancreatic body. The increase in volume of the tail of the gland can be seen in physiological factors, pancreatitis, pancreatic tumor. 1. Physiological factors: it is caused by a few patients with congenital pancreatic development abnormality, and some of them will show pancreatic fullness, but pancreatic function is generally normal, and it will not cause special clinical symptoms, so there is no need for special treatment at this time. 2. Pancreatitis: In this case, pancreatic fullness may be limited or overall, usually caused by pancreatic edema, and oozing can be seen around the pancreas. Patients will have abdominal pain, nausea and vomiting, fever and other symptoms, it is recommended to improve the blood routine, blood, urine amylase, abdominal CT and other definitive diagnosis, to inhibit secretion of pancreatic enzymes, rehydration, anti-infection and other symptomatic treatment. 3. Pancreatic tumor: some benign and malignant tumors can cause local fullness of pancreas, which will be accompanied by different symptoms according to different tumor types. It is recommended to improve abdominal CT, pancreatic magnetic resonance and other examinations to further clarify the diagnosis. It is suggested that patients should go to regular hospitals for consultation and clarification of the cause of the disease, so as to avoid delay in diagnosis and treatment.