The guy toe pain consider gingivitis, gout, osteoarthritis, rheumatoid arthritis, bone fracture, for the cause of the drug treatment, conservative treatment or surgical treatment. 1. Inguinitis: redness and swelling around the toenail, pain is obvious, under the guidance of the doctor to apply anti-inflammatory drugs such as erythromycin, topical fusidic acid, if the effect is not good can be incised and drained. 2. Gout: for sudden redness, swelling and pain in the toes, elevated uric acid in laboratory tests, apply uric acid-lowering drugs such as febuxostat or allopurinol, and apply cold compresses locally. 3. Osteoarthritis: mostly with previous trauma history, joint degeneration, joint narrowing, oral anti-osteoporosis drugs such as bone fairy tablets, topical diclofenac diethylamide cream, ultrasound physiotherapy. 4. Rheumatoid arthritis: symmetrical joint swelling, pain, joint deformation, oral non-steroidal anti-inflammatory drugs, such as diclofenac sodium extended-release tablets or nimesulide capsules. 5. Fracture: history of obvious trauma, local swelling, pain, can not walk, if the fracture is not displaced gypsum fixation for 6 to 8 weeks, fracture displacement line internal fixation surgery. Young people with unexplained toe pain that persists without relief need to go to the hospital for examination and treatment after clarifying the cause.