Itchy urethral symptoms are neurological in nature and can also be clinically termed as neurosis. This is a psychological effect and may be caused by a poor mental state. Many patients will appear anxious, irritable mood, that there may be urethral infection or even stones, or even suspect that they have a sexually transmitted disease, but more anxious and irritable, this mood and increase the symptoms of urethral itching to form a vicious circle. Such a case of clinical examination, diagnosis are more troublesome, to repeatedly test the urine routine, urethral secretion routine and urine and urethral secretion pathogen culture and the whole urinary system ultrasound. In addition, when encountering such patients, it is recommended to do psychological counseling to reduce anxiety and irritability. If necessary, some placebo can also be given, such as vitamin B complex, glutamine, as well as Paracetamol capsules. The patient is advised to practice tai chi and yoga, and to ensure a good work schedule and good and sufficient sleep. This may have a healing effect on the neurogenic itchy urethral sensation.