White head-like particles at the root of the penis may be caused by diseases such as penile pearly papules, penile herpes, folliculitis, condyloma acuminatum and so on. 1. Pearly penile papules: poor local hygiene and cleanliness, circumcision and other reasons can cause pearly penile papules, which can appear as white granules at the root, and may be accompanied by itching discomfort. 2. Penile herpes: when white head-like particles appear at the root of the penis, accompanied by fever, headache, itching and other symptoms, it is considered that penile herpes may occur, and erosion may occur after herpes breaks out to form ulcers. 3. Folliculitis: after the hair follicles at the root of the penis are blocked by sebaceous glands, the infection of bacteria and other pathogens may occur, which may lead to the appearance of whitehead-like particles at the root of the penis, and the localization of pus may occur, or the appearance of tofu dregs-like secretion. 4. Warts: due to the infection of human papilloma virus, the localization can appear like a white head of particles, can also appear papillary, cauliflower-like bumps, often no obvious symptoms.