Cancer of the esophagus is not new to everyone, but cancer of the cardia is an extremely rare type. The cardia is located at the lower end of the esophagus where it connects to the stomach, and there are muscles at the cardia that can stretch and contract to prevent food and acid from entering the stomach from flowing back into the esophagus. Therefore, its symptoms are very similar to those of esophageal cancer in many aspects. In addition, pancreatic cancer is relatively rare, so it is easy for people to confuse the two together. The symptoms of pancreatic cancer and esophageal cancer are very similar, and sometimes it is not easy to distinguish them. The correct definition of pancreatic cancer is adenocarcinoma occurring in the cardia of the stomach, that is, within about 2 cm below the esophagogastric junction line. It is a special type of gastric cancer and should be distinguished from cancer of the lower esophagus. When an enlarged tumor is found in the lower esophagus, an endoscope should be passed through the cardia to observe the cardia, fundus and upper part of the gastric body for any lesions. If there are obvious lesions, it can be diagnosed as cardia cancer, because it is rare to find esophageal cancer and gastric body cardia, but it is quite common to find cardia cancer invading the lower esophagus. If narrowing of the cardia or asymmetric opening is seen, it is mostly suggestive of cardia cancer. If the cardia opening is narrow and the fiber endoscope cannot pass through, and the biopsy is taken from the lower esophagus and the pathology report is adenocarcinoma, it can be diagnosed as cardia cancer invading the lower esophagus. Second, the symptoms of individual esophageal cancer patients are not so obvious. In general, the symptoms of esophageal cancer patients are more obvious, including choking and regurgitation, mucous sputum, vomiting upon entering food, reflux food, difficulty in stammering, and reflex pain of lesion. Symptoms of early stage esophageal cancer: feeling of not being able to swallow food, reflex pain of the lesion, feeling of something in the esophagus, dryness of the throat; swallowing food seems to be in the esophagus all the time, and drinking water also has the same feeling. The manifestations of early pancreatic cancer: often discomfort, slight pain, burning sensation in the upper abdomen and stomach, often with indigestion and loss of appetite, these symptoms often appear intermittently and can be gradually aggravated or transformed. Generally, the symptoms of pancreatic cancer patients are more obvious, which manifest as choking and regurgitation, constant mucous phlegm, vomiting upon entering food, reflux food, difficulty in gulping and reflex pain of lesion. Dysphagia appears later and is much less severe than esophageal cancer, and develops more slowly, and some patients do not have serious dysphagia until the late stage of the disease. Local bleeding is also a very common symptom of cardia cancer. Persistent dull pain in the upper abdomen and back is also a common symptom of advanced pancreatic cancer. Some patients with pancreatic cancer have less obvious symptoms.