The treatment of tibiofibular fracture needs to take into account the specific condition, and can be given general treatment, medication, physiotherapy and other conservative treatments, as well as surgical treatment and other methods. 1. General treatment: including manipulation, splint or plaster fixation, external fixation and heel traction, etc. During the fixation period, the fracture place will recover gradually, during this period, you can’t dismantle the fixation device or move the affected limb by yourself, and can’t use the affected limb to walk until the bone is healed. 2. Medication: Medication is for severe pain after fracture. Non-steroidal painkillers such as ibuprofen and celecoxib can be applied to treat the fracture, and drugs to reduce local tissue edema such as Mai Zhi Ling can also be taken orally. Anticoagulant drugs such as rivaroxaban are also needed to prevent venous thrombosis in the lower limbs. 3. Physiotherapy: Cold compresses can be applied in the early stage of injury to reduce local bleeding and pain symptoms. In the later stage, physical therapy such as hot compresses and baking electricity can be applied to promote local blood circulation, which can facilitate the recovery of the fracture. 4. Surgery: Surgery is mainly used for unstable tibiofibular fracture with important blood vessel and nerve injury, or poorly manipulated and repositioned, in which case surgery is needed to repair the damaged tissues and effective internal fixation. Tibial fibula fracture should go to the hospital in time, complete the relevant examination, clarify the severity of the disease, and follow the doctor’s instructions for standardized treatment, do not blindly use medication and treatment, so as not to delay the condition.