Trazodone hydrochloride tablets for depression and anxiety. Trazodone is an atypical tetracyclic antidepressant whose mechanism of action is selective inhibition of 5-hydroxytryptamine reabsorption. At low doses, trazodone is an antagonist of 5-hydroxytryptamine and at high doses is its agonist. Trazodone does not enhance the action of catecholamines or inhibit monoamine oxidase activity, and has a sedative effect and a slight muscarinic effect. Therefore, the drug is used clinically in patients with depression, in the treatment of patients with or without anxiety. The drug is used with such adverse reactions as dizziness, drowsiness, feeling of fatigue, dry mouth, nausea. It is contraindicated in patients who are allergic to the product; it is contraindicated in patients with severe hepatic insufficiency. The minimum effective dose should be used during the use of the drug; avoid driving vehicles and operating important machinery, etc. after the use of the drug; pregnant and lactating women should be cautious; children or adolescents should be cautious. If you need to use the drug, should be used under the guidance of a specialist, not self-medication to avoid adverse reactions.