Nephrotic syndrome is divided into primary and secondary, and the treatment drugs for primary nephrotic syndrome are mainly glucocorticoid (such as prednisone, methylprednisolone, etc.) and immunosuppressant (such as cyclophosphamide, cyclosporine, etc.), while for secondary nephrotic syndrome, it is also necessary to carry out causative treatment for the primary disease. Glucocorticosteroids mainly play an anti-inflammatory role, which can reduce the damage of inflammation to the kidney. Commonly used are prednisone, methylprednisolone, etc. The principle of use is to start with adequate dosage, slowly reduce the drug, and maintain it for a long time. However, long-term application may lead to infection, osteoporosis and other adverse reactions, need to strengthen the monitoring. And immunosuppressants can block the immune response, avoiding the attack of autoimmune system on the kidney and the deposition of immune complexes in the kidney. This kind of drug is mainly cytotoxic drugs, which can cause liver damage and even induce tumor, so it is necessary to strictly grasp the indications and medication course. Secondary nephrotic syndrome is mainly secondary to diabetes, systemic lupus erythematosus, hepatitis B and other diseases. It needs to be treated for the primary disease. For example, in diabetes mellitus, glucose-lowering drugs (such as metformin, etc.) or insulin should be used to control blood glucose; in systemic lupus erythematosus, hormones and immunosuppressant drugs should be applied; in hepatitis B, antiviral treatment with lamivudine and adefovir should be used. Diuretics (e.g. furosemide, hydrochlorothiazide, etc.) and lipid regulators (e.g. atorvastatin, resuvastatin, etc.) can also be used for symptomatic treatment of edema and hyperlipidemia. If patients find nephrotic syndrome, it is recommended to go to regular hospitals in time and give targeted treatment or therapy under the guidance of doctors.