Spitting out water the next day after drinking alcohol is due to acute gastritis, gastric dysfunction and other factors. There are mucus cells on the surface of the stomach, and their main function is to secrete mucus to protect the stomach wall from being attacked by gastric acid. However, the ethanol in alcohol will break down the secreted mucus after entering the stomach, and at the same time directly cause irritation to the gastric mucosa, especially strong alcohol, the symptoms are more obvious. Many people who drink a lot of alcohol will thus induce an attack of acute gastritis, so it will be accompanied by nausea, vomiting and other symptoms, and even drinking water will cause vomiting. Wine is a stimulating drink, and when it enters the stomach, it will cause irritation to the stomach lining, leading to gastric dysfunction, as well as stomach spasms that cause contractions, so many people experience vomiting due to stomach contractions after drinking wine. For people with more serious vomiting, they can take appropriate vitamin B6 supplements for relief, and intramuscular gastrointestinal injection if necessary.