You can take some antibiotics if the wisdom tooth inflammation causes a systemic reaction, such as fever and discomfort. If the drug is not allergic, both metronidazole and cephalosporin antibiotics are available. 1. Metronidazole has a strong killing effect on gram-positive and negative anaerobic bacteria and fragile bacilli. Adverse reactions Gastrointestinal reactions are common, occasionally neurological symptoms, such as vertigo, ataxia, polyneuritis. Avoid drinking alcohol. 2. Cephalosporins have the advantages of wide antibacterial spectrum, strong antibacterial effect, resistance to penicillinase, high clinical efficacy, low toxicity, less allergic reactions. Adverse reactions are generally mild, occasionally see rash, urticaria, fever. Avoid drinking alcohol. All of the above medications should be used under the guidance of a physician.