The difference between Zhi Bai Di Huang Wan and Liu Wei Di Huang Wan lies in the composition, efficacy and main treatment. 1. Difference in composition and efficacy: Zhi Bai Di Huang Wan is composed of Zhi Mu, Cornus officinalis, Huang Bai, Chinese yam, Zedoaria, and Mudan Pi, etc. Its efficacy is to nourish yin and lower the fire (nourish yin essence and lower the fire). Liu Wei Di Huang Wan is composed of Poria, Chinese yam, Zedoary, Radix Rehmanniae Praeparata, Cornu Cervi Pantotrichum, and Dang Pi, and its effect is to nourish yin and tonify the kidneys. 2. The difference between the main treatment: Zhi Bai Di Huang Wan main treatment of yin deficiency and fire (Yin essence deficiency in the body, the emergence of hyperactive fire) caused by dry mouth and sore throat, tinnitus and spermatorrhea, hot flashes and night sweating (abnormal sweating after going to sleep, waking up sweating to stop), urination (urinary volume is small, dark yellow color), and so on. LIU WEI DI HUANG PILL is used for treating lumbar and knee soreness (a feeling of soreness and weakness in the lumbar and knee regions), dizziness, tinnitus, and bone vapor and tidal fever (a burst of heat, feeling that the heat is coming from inside the bone to the outside) caused by deficiency of kidney yin. The adverse reactions and contraindications of Zhi Bai Di Huang Wan and Liu Wei Di Huang Wan are not known. The drugs should be used under medical supervision, do not blindly self-medicate.