Dry mouth and bitter mouth after getting up in the morning is usually caused by chronic gastroenteritis, oral ulcers or indigestion. 1. Chronic gastroenteritis: due to the slow function of peristalsis, it will increase the chances of bile and gastric acid reflux, causing dry mouth and bitter mouth after getting up in the morning. You can regulate the intestinal flora by taking probiotic drugs such as Bifidobacterium triphylium and lactobacillus tablets to relieve the discomfort. 2. Oral ulcers: refers to the oral mucosa localized ulcerative damage, can cause salivary gland obstruction, resulting in reduced saliva secretion in the mouth, resulting in the morning after getting up after the mouth dry and bitter. You can use watermelon cream, oral ulcers and other drugs to promote the healing of the ulcer surface. 3. Functional dyspepsia: If you go to bed at night and eat too much greasy or indigestible food, resulting in food for a long time in the stomach and intestines to stay, the decomposition of food can produce gas with a peculiar smell, the gas rises to the pharynx, it can cause the morning after getting up after the mouth dry and bitter. It can be relieved by taking drugs that promote gastrointestinal dynamics, such as mosapride and itopride. Patients should take different measures for treatment according to different situations, and should take medicines under the diagnostic advice of doctors, and should not use medicines indiscriminately to avoid aggravating the condition.