HPV infection can be detected by polymerase chain reaction testing, pathohistologic examination, hybridization capture testing, and other modalities such as transcription-mediated amplification.
1. Polymerase Chain Reaction (PCR): The detection of human papilloma virus (HPV) genetic material by PCR can detect HPV-DNA fragments in nucleic acid hybridization-positive specimens. This test is highly sensitive and can not only confirm the diagnosis of HPV infection, but also be able to type HPV infection.
2. Pathohistological examination: Pathohistological examination is to carry out HPV-DNA hybridization of tissues or cells at the site of lesions, which is conducive to the observation of morphological changes in cell tissues and the typing of HPV.
3. Hybridization capture detection: common hybridization capture detection includes nucleic acid blotting in situ hybridization, spot blotting, hybridization capture method and so on. This method of detecting HPV infection has good specificity and sensitivity, and can be typed for HPV.
4. Others: Transcription-mediated amplification, cytological methods, immunohistochemistry and other methods can also be done in normal times to detect the presence of HPV infection.
It is recommended that people suspected of having HPV infection need to consult a doctor in time, and the doctor will choose the appropriate test method according to the patient’s physical condition.