A small granule in the upper eyelid can be caused by conjunctivitis, conjunctival stones, conjunctival granuloma and other conditions. 1. Conjunctivitis:Conjunctivitis will usually cause small particles to appear in the upper eyelid, because the eye is infected by bacteria and viruses, resulting in an inflammatory reaction, and the inflammation stimulates the conjunctival tissue, which can easily lead to lymphocyte hyperplasia, and small particles are formed in the upper eyelid. You can use levofloxacin and tobramycin eye drops under doctor’s supervision. 2. Conjunctival stones: If the body’s metabolism is disturbed, the substances metabolized by the conjunctival tissue may accumulate in the eyes, and small white particles will appear in the eyelid area. Erythromycin ophthalmic ointment and Topaz eye drops can be used under doctor’s supervision. 3. Conjunctival granuloma: often occurs in patients with granuloma or chalazion, if not treated in time, may cause granuloma or chalazion to ulcerate on the surface of the patient’s eyelid, and then irritate the conjunctiva of the eye, which will lead to the proliferation of granulomas, resulting in the appearance of small particles. It can be treated with penicillin and cephalosporin under the guidance of the doctor. It is recommended to strengthen the protection of the eye area in daily life, if you find small granules in the eyelid area, you need to go to the hospital in time for examination, to clarify the cause of the disease, and then carry out targeted treatment.