The pain and burning sensation in the inner thigh is usually caused by herpes virus infection, which enters the body after the body’s immunity is lowered and mainly invades the nerves. Treatment includes improving immunity, ensuring adequate sleep, avoiding overexertion, strengthening physical exercise, applying antiviral drugs such as ganciclovir and acyclovir, and nerve-nourishing drugs such as vitamin B12 and carbamazepine, which can provide significant relief of pain symptoms in a short period of time after treatment.