After taking Dapoxetine the effects of the drug usually last for about 80 minutes, and the duration of sex can be increased to about 3 minutes, the exact duration can be affected by individual factors. Generally, the maximum blood concentration of dapoxetine is reached about 80 minutes after taking the drug, after which the blood concentration begins to decrease, and after 24 hours the blood concentration will decrease to less than 5%. Therefore, to maximize the effect, it is recommended to take one Dapoxetine tablet 1 to 3 hours before the start of sexual intercourse. The latency to ejaculate after erection usually increases from 1 to 2.7 minutes after taking a low dose of dapoxetine tablets. With higher doses of dapoxetine tablets, the latency to ejaculate after erection increases from 1 minute to 3.32 minutes. When using the drug, it should be noted that the drug can cause adverse reactions such as headache, dizziness, nausea, diarrhea, the drug is contraindicated in people with a known allergy to the product, it is prohibited to use it in patients with a significant pathological condition of the heart, and it is prohibited to use it in patients with moderate and severe hepatic injury. The drug should also not be used in conjunction with thioridazine, strong cytochrome P450 3A4 inhibitors, and monoamine oxidase inhibitors. The drug is not recommended for long-term use to avoid resistance and dependence. The exact dosage should be taken under the professional guidance of a doctor.