How long after taking aspirin is also not recommended to drink, to avoid aggravating the damage of the gastrointestinal mucosa. Aspirin belongs to the antiplatelet drugs, the gastric mucosa will cause direct stimulation, at the same time will induce ischemia of the gastrointestinal mucosa, is not conducive to the repair of the damaged gastrointestinal mucosa. Alcohol on the gastrointestinal mucosa will also cause stimulation, oral aspirin after drinking alcohol, may lead to gastrointestinal mucosa damage to the degree of aggravation, induced gastric ulcers or even peptic bleeding occurs. It is not recommended to drink alcohol at any time while taking aspirin to minimize damage to the gastrointestinal mucosa and prevent serious complications. Adverse reactions that may occur during the administration of aspirin include stomach pain, bloating, dyspnea, gastrointestinal bleeding, bleeding from the mucous membranes of the skin, etc. It is contraindicated in patients who are allergic to the components of the medication, aspirin-associated asthma, active bleeding, aspirin-associated angioedema, and major surgeries within a short period of time. Therefore, the use of medication should be under the guidance of a physician.