Gray nails, also known as nail fungus disease or onychomycosis, are usually curable and are usually treated through measures such as topical medications and systemic medications. 1. Topical medication: Since the medication does not easily penetrate the nail plate, the therapeutic effect is limited, and it is recommended to combine the treatment with oral antifungal medication. Topical medication can be used to remove the nail as much as possible with a knife or nail file, or use warm water to soften the perinail tissue, and then apply antifungal medication, such as cycloheximide cream, amorphophallus powder, and so on. 2. Systemic medication: mainly through oral antifungal drug treatment, common drugs such as itraconazole, terbinafine tablets, etc., the use of antifungal drugs, need to be under the guidance of the doctor in full dosage, the full course of use, should pay attention to the monitoring of the drug’s adverse drug reactions, such as drug-related liver injury. Allergic to the drug is forbidden to use, combined with other drugs for the treatment of onychomycosis, should consult the attending physician in detail. It is recommended that patients with gray fingernails go to the hospital for examination in a timely manner, and all drugs should be used under the guidance of a professional doctor.