The most dangerous time after pancreaticoduodenectomy is about 1 week after surgery, when bleeding is more likely to occur, but the specifics need to vary from person to person. In the case of intra-abdominal bleeding, it often occurs within 24-48 hours after surgery and is mainly due to improper intraoperative management of the peripancreatic artery of the stomach. If the postoperative bleeding is small, close observation is recommended; if the bleeding is large and cannot be stopped, immediate surgical exploration should be performed. In case of gastrointestinal bleeding, such as anastomotic bleeding and pancreatic fluid from pancreatic fistula eroding the blood vessels, it usually occurs within 1 week after surgery and can lead to hemorrhage or even life-threatening in severe cases. Therefore, after pancreaticoduodenectomy, patients need to be closely observed for bleeding and other conditions. In addition, patients recovering from pancreaticoduodenectomy may also have digestive problems, such as indigestion, and it is recommended to visit the general surgery department of the hospital promptly if necessary.