(Disclaimer: This article is only for popular science purposes, in order to protect the privacy of patients, the following content of the relevant information has been processed) Abstract: The patient has a history of gastric disease, recently appeared epigastric pain, abdominal distension and other symptoms, taking medication is ineffective, the diagnosis of the duodenal polyps, gastroenteroscopy polypectomy, postoperative mental status is good, follow up without recurrence. Duodenal polyp is a relatively common gastrointestinal polyposis, the first symptoms are mostly abdominal discomfort, belching, acid reflux, etc., delayed condition may lead to polyp malignant transformation, the abnormalities immediately excision, the general recovery effect is good. Basic information] Male, 55 years old [Type of disease] Duodenal polyp [Hospital] The First Affiliated Hospital of Kunming Medical University [Time of consultation] November 2021 [Treatment plan] Gastroenteroscopic polypectomy + medication (tranexamic acid + omeprazole acid suppression + aluminum thioglycollate) [Treatment cycle] Hospitalization for 4 days, six months of follow up [Effect of treatment] Rehabilitation discharged from the hospital, no follow-up review and follow-up visits Mr. Wang was treated in our hospital for abdominal pain 2 years ago, diagnosed with gastric ulcer and duodenal ulcer, and was discharged. Recently, Mr. Wang felt vague pain and distension in the upper abdomen, and he came to our hospital because he was not satisfied with the treatment of omeprazole. Since the beginning of his illness, Mr. Wang’s spirit, appetite, sleep, normal bowel movements, no significant changes in body weight, currently vague pain in the epigastric region, abdominal distension, the lower part of the raphe is more pronounced, can be tolerated, was paroxysmal, with little relationship with the position, feeding, epigastric pressure pain, the rest of the physical examination did not see any significant abnormality, the e-gastroscopy showed that the duodenal bulb of the single polyp, chronic superficial gastritis. Combining Mr. Wang’s medical history, symptoms, signs and examination, he was diagnosed with duodenal polyp, and was admitted to our department after completing the nucleic acid test. After Mr. Wang was admitted to the hospital, he was temporarily given symptomatic supportive treatment such as gastric protection and rehydration, and was actively perfected the 3 major routine, liver and kidney function, electrolytes, coagulation function, electrocardiogram, chest X-ray, ultrasound, upper gastrointestinal tract imaging and other related examinations, which excluded the heart, lungs, and other abdominal organs, and further diagnosed as duodenal polyp. Mr. Wang heard that intestinal polyps have the possibility of malignancy, so he requested to try to resect, in order to meet the patient’s demand, after excluding contraindications to surgery, it was decided to perform electronic gastroenteroscopy polypectomy on the following day, during the operation in the duodenal bulb to excise a 0.2 × 0.1 × 0.1 cm size polyp, sent to the pathology examination, and be given to the hemostatic clip clamped the local mucosa to stop the bleeding, and return to the ward, to be given to the aminomethylcyclopentanoic acid to stop the hemorrhage, omeprazole inhibition of He returned to the ward and was treated with tranexamic acid to stop bleeding, omeprazole to inhibit gastric acid and aluminum thiosulphate to protect the mucous membrane. He was closely monitored for bowel movements and was discharged from the hospital after a 3-month review of the polyp, as the pathology of the polyp showed that the polyp was benign adenomatous and had a possibility of recurrence. After gastroenteroscopic polypectomy, Mr. Wang’s vital signs were stable. After returning to the ward, he was put on a liquid diet after 24 hours of fasting and water fasting without any obvious discomfort, and the pathological examination clearly showed that the nature of the polyp was benign adenomatous polyp, which did not require any special treatment. The patient was discharged from the hospital on the fourth day of hospitalization, with good mental status, no nausea, abdominal pain, abdominal distension and other uncomfortable symptoms, basically normal diet and bowel movements, and no obvious abnormality in the follow-up examination. There was no recurrence after half a year’s review and follow-up. Precautions 1. I am truly happy for the patient’s recovery. In addition, the patient should pay attention to improve the diet after discharge, eat small meals, ensure adequate chewing, reduce the burden on the stomach and intestines, choose less gas-producing, easy-to-digest food, avoid high-salt, high-fat, high-sugar diets, preferred steaming cooking, avoid fried food, quit smoking and alcohol; 2, the patient should pay attention to the combination of work and rest, regular work and rest, try to avoid strenuous exercise, should be based on aerobic exercise such as walking, jogging, rest, avoid staying up late, and after meals, avoid the recurrence of the disease. Rest, avoid staying up late, do not lie in bed immediately after meals, pay attention to personal warmth, avoid colds; 3, patients continue to take omeprazole, aluminum thioglycollate to inhibit gastric acid and protect the mucosa after discharge from the hospital, if there is abdominal pain, black stools, etc., seek medical attention, and review gastroscopy 3 months after discharge. V. Personal perception Duodenal polyps are relatively common, some patients with duodenal polyps can strengthen the follow-up observation, not to be dealt with, but most patients are recommended surgical resection. 1.Strengthening follow-up: it is applicable to patients with small polyps and no clinical manifestations, and can be left untreated after excluding the risk of cancer, but attention should be paid to strengthen the follow-up and regular rechecking. 2.Surgical resection: there is no specific drug for duodenal polyps, only for symptomatic treatment, so when patients have symptoms or polyps with risk, they should be surgically resected immediately, such as Mr. Wang in the article, who can achieve the effect of clinical cure after surgical treatment, but also need to be regularly rechecked after the operation. Daily life should have a good diet and bowel habits, do not smoke and do not drink, in order to prevent the reoccurrence of duodenal polyps, if there is discomfort should be timely medical treatment, follow the doctor’s instructions for symptomatic treatment.