Supplementation of Jarrah, i.e., estradiol valerate, in vitro pregnancy this drug is usually taken until about 10 weeks, but there are individual differences. In vitro transfer refers to in vitro fertilization-embryo transfer technique, before embryo transfer to prepare the endometrium in advance, can be supplemented with estradiol valerate under the guidance of the doctor at the beginning of the menstrual period, when the ultrasound examination suggests that the thickness of the endometrium reaches more than 0.7cm and there are sufficient levels of estrogen can be transplanted, generally take to about 10 weeks can gradually stop taking this drug. Contraindications such as hepatic and renal insufficiency should be ruled out before taking estradiol valerate. Since taking the drug may increase the occurrence of breast cancer, ovarian cancer and other side effects in women, the drug should always be taken under doctor’s supervision. Generally, the dosage can be gradually reduced after pregnancy is confirmed by blood pregnancy test after transplantation, and the drug can be gradually discontinued as prescribed by the doctor when the ultrasound examination suggests good development of fetal buds and fetal heart.