Thumb pain may be caused by trauma, tenosynovitis, tenosynovial cyst, synovitis and hemangioblastoma. 1. Trauma: when the thumb is crushed by collision or impact, it will lead to damage to the muscle and soft tissue of the thumb or bone joints, resulting in localized edema and pain in the thumb, and if there is a fracture, the movement of the finger joints will be restricted. 2. Tenosynovitis: tenosynovitis can also cause pain in the little thumb, this disease is usually due to excessive fatigue of the fingers, thus causing aseptic inflammation of the tendon sheath. The patient may also experience ringing of the fingers, which may lead to joint movement restriction in severe cases. 3. Tendon cysts: Cystic growths in the tendon sheath compress the nerves in the thumb, causing pain in the thumb. 4. Synovitis: mainly in the interphalangeal joints, resulting in swelling and pain on palpation. 5. hemangioblastoma: pain in the little thumb, also need to identify with other occupying lesions, such as hemangioblastoma, mainly in the nail bed of the end of the finger below the pain. The site of pain is clearer, and it appears under cold water stimulation, and it is painful when touching, while it is painless when not touching or not touching. Pain in the little finger, also need to rule out peripheral microcirculatory disorders, such as poor peripheral circulation due to diabetes, or nerve compression presenting as peripheral nerve tingling. Thumb pain may also be due to rheumatism, rheumatoid arthritis, gout and other diseases, should be timely medical examination and treatment.