Excessive sebaceous gland secretion and clogged pores may be caused by acne, seborrheic dermatitis, rosacea and other diseases, which can be treated by medication and general treatment. 1. Acne: Patients with acne may have exuberant secretion of sebaceous glands and clogged pores, and can apply benzoyl peroxide gel to kill Propionibacterium acnes, or apply retinoic acid ointment to improve follicular sebaceous gland duct keratinization, and can also take doxycycline and minocycline orally to control the infection when secondary bacterial infections of the skin occur. 2. Seborrheic dermatitis: seborrheic dermatitis patients will also appear sebaceous gland secretion, pore clogging phenomenon, you can use sulfur ointment, salicylic acid preparations and other drugs to treat, local itching, you can take antihistamine drugs to sedate the itch, such as loratadine, cetirizine, etc., and if necessary, you can also be applied to hydrocortisone ointment, compound dexamethasone cream and other medications to treat. 3. Rosacea: Excessive sebaceous gland secretion and clogged pores may also be caused by mite dermatitis, which can be treated by topical application of clindamycin metronidazole ointment, as well as oral antibiotic medication, such as doxycycline, etc.; severe cases can also be treated with laser therapy, intense pulsed light therapy, and surgical treatment. If the sebaceous gland secretion is exuberant and the pores are clogged, it is recommended to go to the dermatology department of the regular hospital for a clear diagnosis and treatment after finding out the cause.