Hormonal creams are mainly creams containing steroid hormones, which have anti-inflammatory and anti-immune effects, so they have a relatively fast effect on many skin diseases. As soon as the cream is applied, the skin will be improved, but after stopping the medication, the symptoms will come back, but will be aggravated. After long-term topical application of hormone creams, hormones will be absorbed into the body through the skin, which will cause a series of problems, because a large amount of hormone intake from the skin will affect the blood pressure, blood sugar, blood lipids, and even lead to osteoporosis and other problems. The level of adrenocorticotropic hormone secretion in the body is relatively low. Once you stop using hormones, the function of your own adrenal cortex will not be fully restored, and acute adrenal cortical insufficiency will occur, which may even endanger the life of the patient in serious cases.