Treatment of nodular itch is as follows: First, medication, topical hormone ointment, such as terbinafine cream, miconazole cream, etc., if the number is large, can be treated by local injection of hormones, such as tretinoin injection, serious can be combined with oral thalidomide tablets, can not be cured in time to the hospital for laser cauterization or liquid nitrogen freezing treatment. Secondly, if itching is caused, antihistamines can be used to relieve the symptoms, such as paracetamol, doxepin, loratadine, etc. Third, if skin hyperplasia occurs, oral vitamin capsules or isotretinoin soft capsules should be taken. Fourth, if it is caused by allergies, avoid contact with allergens first, and then take oral wet toxin clear, levofloxacin, cetirizine and other drugs on treatment. Fifth, pay attention to the usual care, pay attention to local hygiene, keep dry, eat more vegetables and fruits. Pay attention to good rest, maintain a good mood, regular life, do not scratch the affected area, it will lead to increased itching, may also cause infection, patients should regularly go to the hospital for review.