Male breast enlargement with lumps can choose drug treatment, if necessary, need to take surgical treatment. 1. Medication: Male breast enlargement with lumps is mainly related to the high estrogen level in the body, so you can use medication to improve the symptoms, such as citrate tamoxifen tablets, testosterone, anastrozole tablets and so on. 2. Surgery: If the male breast enlargement with lumps is more serious, or even cause gynecomastia, surgery can be considered to take surgical treatment, through the surgery to carry out subcutaneous gland removal. In most cases, male breast enlargement can get better on its own; for those who have primary causes, such as taking certain medications, they can usually be relieved after stopping the medication, but there are rare cases of breast enlargement with the possibility of cancer, which should be surgically removed immediately. After the phenomenon of male breast hyperplasia with lumps, it is recommended that patients go to the hospital in a timely manner, follow the doctor’s guidance and recommendations for related treatment, the above drugs need to be used under the guidance of the doctor, do not treat indiscriminately, so as not to lead to adverse consequences.