In acute pulmonary edema, the concentration of oxygen plus alcohol has generally been between 20% and 30% in past treatments. However, there is no clear evidence to suggest that oxygen with alcohol is needed for acute pulmonary edema. In alcohol humidification inhalation of oxygen in the treatment of pulmonary edema, usually more than 70 years ago, but this exploration. Effectiveness and safety of the lack of appropriate scientific evidence, this is also a relative failure of the exploration, there is no evidence can be on acute pulmonary edema oxygen inhalation is to promote the role of remission, there is no evidence, and does not recommend such use of alcohol to oxygen therapy. Under the current evidence-based medicine, cardiopulmonary edema caused by acute heart failure should follow the guidelines and adopt individualized management strategies, and the use of alcohol is not recommended.