After taking drugs, take sperm before laboratory tests or not, generally need to take drugs according to the type of drugs, drugs use days related, specific as follows: 1. drug type: if you take anti-inflammatory drugs after a cold, such as cephalosporins, generally does not affect the quality of sperm, can be carried out sperm extraction; but if you take drugs with inhibition of sperm maturation or toxicity of sperm, such as anti-androgenic compounds methyl chlortalidone acetate, sperm extraction is recommended to improve the relevant laboratory tests, to make clear the quality of the sperm and the severity of the impact. 2. The number of days the drug has been used: when the drug is taken for a short period of time and has no obvious effect on sperm quality, no laboratory tests can be conducted, but when the drug has been used for too many days, it is generally recommended that tests be conducted before sperm collection. After taking the drug, there are uncomfortable symptoms, it is recommended to consult a doctor in a timely manner, and it is generally recommended to complete the relevant examinations before sperm extraction to clarify whether there is any effect on sperm, do not be negligent, so as not to affect the quality of sperm.