Colonic tubular adenoma with mild to moderate atypical hyperplasia has a certain risk of recurrence after surgical resection, and it can also recur in situ after surgical resection. Patients need to undergo regular rechecking after surgery, and carry out standardized treatment under the guidance of doctors after surgery to avoid recurrence as much as possible, and actively treat recurrence if any. Tubular adenoma with atypical hyperplasia of colon belongs to precancerous lesion, it is benign lesion, but there is a risk of malignant transformation if treatment is not timely, early and clear diagnosis should be carried out as soon as possible after surgical resection, and after resection, it can effectively prevent deterioration. For the patients after surgical treatment, they need to cultivate a good habit of life as well as dietary habits, and have regular recheckups, and actively treat it, which can play certain preventive roles. Patients with colonic tubular adenoma need to undergo regular review after surgery to detect possible malignant changes in time and avoid delaying the condition.