If barrett’s esophagus has undergone chemosis, it is difficult to reverse or prevent the change by medication, and its treatment is mainly surgical.
There is no conclusive clinical evidence to indicate which class of drugs can reverse barrett’s esophagus chemosis of columnar epithelium, or there is conclusive evidence to prove that it can prevent barrett’s esophagus from becoming cancerous, therefore, proton pump inhibitors such as omeprazole are limited to improve the symptom of gastroesophageal reflux. Prompt surgical intervention is recommended for the detection of barrett’s esophagus metaplasia, especially intestinal epithelial metaplasia.
Surgical treatment modalities for barrett’s esophagus include endoscopic mucosal dissection, endoscopic mucosal resection, and other surgical treatments. Pathologic examination of the resected tissue is required after surgery, and it is recommended to review the lesion every 3 years if the lesion is less than 3 cm or accompanied by intestinal epithelial hyperplasia, and every 2 years if the lesion is more than 3 cm.
The appearance of barrett’s esophagus plus timely visit to the hospital; omeprazole and other proton pump inhibitors need to be used under the guidance of clinicians, prohibit unauthorized use of drugs.