Corneal infection is manifested as corneal fungal moss or ulcers, subcutaneous tissue type dark filamentous mycosis can be seen in the subcutaneous tissue with thin pus, cysts with exudate, if the cyst wall excision is incomplete, leaving a sinus tract, can not heal for a long time. Dark filamentous mycosis is a group of dark fungi caused by the tissue with dark mycelium as a characteristic of the skin, subcutaneous tissue or systemic infection. 1974 Ajello proposed this name. Dark colored mycosis has been reported in scattered cases around the world, but mostly seen in the tropics. In recent years in Shandong, northeast China and Zhanjiang and other places there are reports of disseminated cases. Pathogenic route is mainly exogenous infection and conditional pathogenic infection. The route of infection may be the implantation of the pathogenic fungus through a skin break or inhalation of fungal spores. Clinical manifestations are superficial ulcers, petechiae, brownish-black spots or wart-like growths with slight itching or mild swelling and pain, and some may have no conscious symptoms. Diagnosis relies on mycological examination and histopathological examination. Most of them are not sensitive to antifungal drugs and have poor efficacy. What are the symptoms that can be easily confused with it? Sometimes need to be distinguished from staining bacteriophage and hyaline filariasis. 1, coloring bacteriosis by dark-colored fungi (including bipolar mold genus, branched bottle mold genus, mycosphaerella genus, Delethorax genus, external bottle mold genus, color-producing bacterium genus, bottle mold genus, branched spore mold genus, Ochroconis, nasal Trichoderma genus, linear tamerella genus and Wan’s genus) caused by the subcutaneous tissue, sinus, brain and other tissue infections. The common symptoms of the disease are papules, ulcers, itching, the following is a compilation of many articles for your information, although it can not solve the disease, but can increase your understanding of the disease can also play a role in health care prevention. 2, hyalohyphomycosis (Hyalohyphomycosis) is a group of non-dark fungi caused by the histology of hyaline mycelium as a characteristic of infectious diseases. In 1982, Ajello and McGinnis proposed the name of the disease corresponding to the darker filamentous mycoses. The significance of these two disease names is that they can continuously accommodate new pathogenic fungi, without the need to establish a disease name for each new species. However, the pathogenic fungus has been named and widely used, such as Aspergillosis still use the original name. Dark filamentous mycoses include palm black spot and black hair nodular disease. Can be manifested as shallow ulcers, petechiae, brown-black spots or wart-like growths, slightly itchy or mildly painful, some can be no conscious symptoms. Palmar melanosis is a brown to black non-scaly patch on the palm and metatarsal areas. Occasionally, it may spread to the neck and chest. Black hair nodular disease is the formation of small ovoid nodules on the hair shaft, hard as stone, like lice eggs hanging or encrusted in the hair shaft, black. It is not easy to see clearly with the naked eye. When rubbed with a finger, it looks like sand. It mainly affects the hair and to a lesser extent the eyebrows and eyelashes. Corneal infections are characterized by fungal moss or ulcers in the cornea, and the patient feels photophobia, lacrimation and visual impairment. The lacrimal gland infection is characterized by lacrimal obstruction, pus overflow, and local granulomatous damage. Dark seromycosis often has isolated, deep in the subcutaneous or muscle abscesses or cysts, lesions can be apricot kernel size or several centimeters, or even the entire chest large plaques. At this time, the skin is often involved in maroon or gray-black, feel the infiltration, rough surface, generally not broken, biopsy can be seen in the subcutaneous tissue with thin pus, cysts with exudate, if the cyst wall is not fully excised, leaving a sinus tract, can not heal for a long time.