The method of boosting platelets depends on the different causes of platelet decline. Platelet drop can be caused by primary immune thrombocytopenia, aplastic anemia, and acute leukemia. It can be treated with general therapy, immunoglobulin and other medications, and hematopoietic stem cell transplantation if necessary.
1. Primary immune thrombocytopenia (ITP): general application of glucocorticosteroids including prednisone, dexamethasone, etc. is the drug of choice for ITP. When platelet drop is very obvious, it can be combined with immunoglobulin for treatment. Refractory ITP can also be treated with second-line drug therapy, such as rituximab and eltrombopag. Splenectomy is feasible when drug treatment is ineffective.
2. Aplastic anemia (re-infections): For severe re-infections, allogeneic stem cell transplantation should be preferred when available. Meanwhile, supportive and symptomatic treatment should be given, such as active anti-infection, platelet and red blood cell transfusion to prevent bleeding and infection. For non-severe cataracts, cyclosporine treatment should be preferred, and oral androgens and other drugs to promote hematopoiesis should be given at the same time.
3. Acute leukemia: a series of malignant blood diseases, including acute leukemia, can also cause thrombocytopenia, and need to be promptly treated with drug chemotherapy, such as cytarabine, Zoerythromycin and so on.
There are other causes of thrombocytopenia, such as systemic lupus erythematosus, severe liver disease, etc. It is recommended to consult a doctor in time to find out the cause and treat the cause. The above medication is in accordance with the doctor’s prescription.