The causes of red raised flesh grains on the tongue and painful are usually associated with tongue body mouth ulcers, tongue burns, tongue papillitis, oral acromegaly, tongue herpes and other factors. According to the typical characteristics of different diseases, patients can first preliminary self-diagnosis and deal with them accordingly, but when the symptoms are more serious, they should still go to the hospital for systematic treatment as soon as possible: 1. Tongue body mouth ulcers: When mouth ulcers occur on the tongue, they can be manifested as red raised flesh grains, and accompanied by significant pain. The disease gradually develops and may appear as a grayish or yellowish broken point with a depressed middle and red edges. Patients can spray watermelon cream, mouth ulcer dispersion, and supplement vitamin C and vitamin B to promote the healing of the lesion. The patient can use light salt water to rinse the mouth and apply iodine glycerin to promote the symptoms to subside; 3, tongue papillitis: the patient mostly shows a red raised flesh grain on the tongue. It is painful and accompanied by enlargement of the tongue, and in severe cases, it may even affect swallowing and speech function. This type of patients generally need anti-inflammatory pain medication, such as gargling chlorhexidine solution, need to pay attention to periodontitis and incisors to fill the patient prohibited, the symptoms do not ease for a long time can be considered to the hospital for surgical treatment; 4, oral acromegaly: that occurs in the oral area of the acromegaly, mainly caused by human papillomavirus infection. The main performance for the tongue belly, tongue, tongue back, tongue lateral edge and other parts of the cauliflower-shaped or papillary redundancy, can be shown as a red bump, while accompanied by pain, most with other parts of the genital, anal and other lesions. Patients can use topical acyclovir gel, or take acyclovir tablets for antiviral treatment; 6, other: In addition, tongue mucosal hyperplasia, tongue polyps, tongue hemangioma, tongue papilloma, etc., can also be manifested as red raised granules on the tongue, accompanied by significant pain, such diseases usually need to take surgical treatment. Since there are many diseases that cause painful red bumps on the tongue, patients with these symptoms are advised to go to the hospital as soon as possible for a clear diagnosis and appropriate treatment.