The so-called grease grain is not currently a clear concept of definition, may be cornu rashes, sweat pipe tumor, or closed mouth acne, different diseases treatment principles are different. 1. Corns: a kind of retention cyst on the surface of the skin, the removal method is mainly laser treatment. 2. Sweat duct tumor: also known as sweat duct cystic adenoma, is located in the epidermis of the small sweat gland ducts of benign tumors, to remove the method of physical therapy. In general, carbon dioxide laser treatment can be chosen to remove. 3. Closed mouth acne: also known as whitehead acne, is due to the follicle mouth keratinization or pore blockage caused by secretion can not be normally discharged and the formation of a kind of skin disease, remove the method is to use topical dissolution of keratin medication, such as retinoic acid cream, or through the fruit acid resurfacing and other treatments, to remove the closed mouth acne. Due to the complexity of the cause of the condition, a doctor’s consultation is required for specific cases, and medication should be administered under the doctor’s supervision.