Paeonia lactiflora and Glycyrrhiza glabra Tang is a traditional Chinese medicine formula composed of two herbs: Paeonia lactiflora and Radix et Rhizoma Glycyrrhizae. Paeonia lactiflora and Radix et Rhizoma Glycyrrhizae Sinensis Tang is from the Treatise on Typhoid Fever and is mainly composed of two herbs: Paeonia lactiflora nourishes blood, benefits yin, and eases pain (relieves urgent pain); Radix et Rhizoma Glycyrrhizae Sinensis replenishes the middle Jiaozhong and benefits the qi (treats deficiency of qi by replenishing the spleen), which helps to provide a source of qi and blood and can also ease pain. Combined, they are mainly effective in nourishing blood and benefiting yin, and relieving emergency pain. Paeonia lactiflora and Glycyrrhiza glabra soup can be used in treating contracture of legs and feet or pain in the abdomen caused by deficiency of Yin and Blood and poor Blood circulation. This formula is an ancient Chinese medicine prescription, the specific use should also be combined with the patient’s own condition in the physician’s diagnosis under the guidance of the addition, subtraction and customization of the application, not blindly self-medication.