Inflammation and pus in the nail groove is a symptom of a purulent bacterial infection of the nail groove and surrounding tissues, usually caused by Staphylococcus aureus. Inflammation and pus in the nail groove is usually caused by ingrown nails, improper nail cutting and other reasons. It is important to treat the condition promptly so that the symptoms do not worsen. Patients with inflamed and pus-filled onychomycosis may have redness, swelling, heat and pain, and produce pus due to the development of inflammation. At this time, white pus spots may appear and be accompanied by a fluctuating sensation, which extends to the root of the nail, resulting in a subnail abscess. Patients with an inflamed and pus-filled nail should undergo a nail drainage procedure to drain the nail. Keep the skin clean to avoid infection, minimize scratching of the lesion, don’t go too deep when clipping nails, try to use nail clippers when barbs appear, don’t tear it with your hands, and consult a doctor when symptoms worsen.