The criteria for remission of multiple myeloma include a variety of clinical symptoms reduction, hematologic remission, and reduction of myeloma diameter. 1. Reduction of clinical symptoms: for example, symptoms such as elevated blood calcium, liver function impairment, bone pain, etc. have been alleviated. 2. Hematologic remission: for example, M protein is reduced by more than 90% or disappears, serum free light chain is restored to normal level, blood and urine immunoelectrophoresis are negative, and monoclonal plasma cells in bone marrow disappear. 3. Reduction of myeloma diameter: the diameter of the bone lesion is reduced compared with the previous one. The efficacy of multiple myeloma patients after treatment should be judged under the guidance of physicians, and they need to be regularly rechecked during the treatment period and actively cooperate with doctors.